产品货号:
Z26515
中文名称:
SHISA3抗体
英文名称:
Anti-SHISA3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SHISA3 Antibody |
指标别名 | hShisa3,Protein shisa-3 homolog |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | SHISA3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | SHISA3 antibody was raised against a 15 amino acid peptide near the center of human SHISA3.The immunogen is located within amino acids 120 - 170 of SHISA3. |
计算分子量 | 26kDa |
成分 | SHISA3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | SHISA3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | SHISA3 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling.The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region.Its founding member,Xenopus Shisa,promotes head development by antagonizing Wnt and FGF signaling.Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface.Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation. |
Uniprot ID | A0PJX4 |
基因名全称 | Shisa homolog 3 (Xenopus laevis) |
蛋白名全称 | Shisa homolog 3 (Xenopus laevis) |
推荐稀释比 | SHISA3 Antibody can be used for detection of SHISA3 by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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